Wednesday, November 27, 2019

Unit 3 Firac Case Brief free essay sample

Ashley E. Parramore Introduction to Legal Analysis and Writing PA 205 August 8, 2011 Donnelly V. Rees Case Brief. Donnelly V. Rees Case Name: Donnelly V. Rees, 141 Cal. 56 (1903) Court: California Supreme Court FACTS: An action may be maintained by the sole heir of a deceased person to set aside a deed procured from the deceased without consideration by the fraudulent practices of the defendants and their undue influence over the deceased, who was known to be a habitual drunkard for more than five years before the execution of the deed. ISSUE: The plaintiff was not required to make any payments on account of an alleged bill against the grantor, or for moneys alleged to have been advanced to him subsequently to the alleged transaction, where these matters cannot be regarded as connected with the transaction. RULE: Section 2224 of the California civil Code (1) The defendant gained the land by fraud. (2) By undue influence, and are therefore or, rather each is an involuntary trustee of the thing gained. We will write a custom essay sample on Unit 3 Firac Case Brief or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page 3) The same result follows, because they gained the thing by the violation of a trust. Upon either of these principles, therefore, the plaintiff is entitled to recover, unless precluded as is contended by the appellants. ANALYSIS: The court cited in the decisions of Civ. Code, sec. 2219 Pierce V. Robinson, 13 cal. 127 Kimball V. Tripp, 136 Cal. 634, 635 Knight V. Tripp, 121 Cal. 674 Davies V. Otty, 35 Beav. 213 CONCLUSION: It was not necessary that the plaintiff should pay to the defendants the amount of their alleged bill, or to O’Brien the amount alleged to have been advanced to Kean subsequently to the transaction or that the court should so adjudge under the findings which we have held to be sustained by the evidence. These matters cannot be regarded as being connected with the transaction Guidici v. Guidici Case Brief Guidici v Guidici Case Name: Guidici V. Guidici 2 Cal. 2d 497 1935 Court: California Supreme Court FACTS: In this action to cancel a deed to real property, the evidence that plaintiff at the time of signing the deed was in such a state of mind, due to long and excessive drinking of intoxicating liquor, that he did not know what he was doing, and that he had no recollection of signing the deed, was sufficient to support the finding that he was mentally incapable, at that time, of understanding the nature of his act in the signing and execution of said deed, and such finding could not be disturbed on appeal even though there was considerable conflict in the evidence. ISSUE: While marriage is a good consideration for a deed, or for a contract generally, if such a deed is executed by the grantor at a time when he is incapable of understanding his act in the execution thereof, by reason of long and excessive drinking, and the marriage is entered into about an hour later, while he is in the same state of mind, it cannot be said that the marriage ceremony forms a valid consideration for the execution of said deed. RULE: The defendant was a woman of over fifty years of age at the time. She had been married twice before, and she admitted that she was marrying the plaintiff as a business proposition. At no time did she manifest any affection toward the plaintiff. She evidently reposed but little confidence in him, or was aware of his intoxicated condition, as she absolutely refused, at the suggestion of the attorney, to proceed with the marriage ceremony until the deed to plaintiffs valuable farm was signed and delivered to her. These matters were undoubtedly given careful consideration by the trial judge who, after a review of all the evidence with the parties before him and an opportunity to observe their conduct and demeanor, believed the testimony of the plaintiff and his witnesses, and made findings favorable to him. According to the well-established rule in cases involving conflicting evidence, the findings of the trial court must be sustained on appeal. ANALYSIS: A person who at the time of making a contract is completely intoxicated may avoid his contract notwithstanding the fact that his intoxicated condition may have been caused by his voluntary act and not by the contrivance of the other party to the contract. (6 Ruling Case Law, p. 595. ) CONCLUSION: It is not necessary for us to give any xtended consideration to the further contention of the defendant that there is no evidence to support the finding of the trial court that there was no consideration for the deed. It is, of course, true that marriage is a good consideration for a deed, or for a contract generally, but if the deed was executed by the grantor at a time when he was incapable of understanding his act in the execution thereof, his marriage was entered into while in the same state of mind. If one was not binding upon him by reason of the fact that he was mentally incompetent of entering into a valid contract the other may be avoided for the same reason. In these circumstances it cannot be said that the marriage ceremony to which the plaintiff and defendant were parties formed a valid consideration for the execution of said deed. The judgment is affirmed.

Sunday, November 24, 2019

Report Card Comments for Elementary Teachers

Report Card Comments for Elementary Teachers When writing report card comments, focus on the students existing strengths and look for ways to motivate the student to improve in areas of weakness by providing advice. The following phrases and statements can help you tailor your comments for each specific student. Writing report card comments designed to instill ambition within students can empower them to make positive changes. Try to provide specific examples whenever you can to make your report card comments more personal. Key Takeaways: Report Card Comments Stress positive attributesUse words such as requires, struggles, or seldom to show when a child needs extra helpIntroduce areas in need of work in a way that wont make parents feel like youre criticizing the student unnecessarily, for example, list negative comments under a comments section titled goals to work on Supportive and detailed comments can provide parents with ways to partner with you to make students feel empowered to do better Attitude and Personality Phrases should present information n a straightforward manner about the students classroom temperament, giving suggestions for improvements when possible: Has a good attitude toward school.Is an enthusiastic learner who seems to enjoy school.Strives to reach his full potential.Shows initiative and thinks things through for herself.Exhibits a positive outlook and attitude in the classroom.Is a sweet and cooperative child.Is self-confident and has excellent manners.Is honest and trustworthy in dealings with others.Is developing a better attitude toward schoolwork this year.Needs to improve classroom attitude by learning to better collaborate with classmates.Needs to work on sharing more with others and being a better friend. Comments should be both celebratory and constructive when appropriate. Give examples of what works well for students, recognize areas in which they truly excel, and provide information not only on what needs to be improved but how the student can improve in those areas. Continues to make nice progress this year concerning...As we discussed in our last parent-teacher conference, [your childs] attitude toward the basic skills is...I will continue to need your help and support in order for [your child] to overcome his attitude and social difficulties. He will find school a much more pleasant place if he/she can make a positive effort in this area.[Your childs] attitude has continued to improve. Thank you for your support and cooperation.[Your child] has shown a good attitude about trying to improve in [this subject]. I am hoping this recent interest and improvement will continue throughout the school year. Participation and Behavior Spend time reflecting not just on grades but also the students actions in class. Participation is often a significant portion of the grading model, and your comments should address the level of a students participation, such as remains an active learner throughout the school day and is enthusiastic about participating. Comments should also address a students behavior, both positive and negative. Takes an active role in discussions.Needs to actively participate in classroom discussion.Listens attentively to the responses of others.Is courteous and shows good manners in the classroom.Consistently cooperates with the teacher and other students.Is kind and helpful to everyone in the classroom.Caring, kind, and eager to please.Needs to listen to directions.Needs to work on staying focused and on task.Needs to work on not distracting others during class. Time Management and Work Habits Students who are always well-prepared for class and have strong organization study habits can benefit from being reminded that this simple, yet important, skill is recognized and appreciated. Similarly, students who arent prepared, rush their work, or need to stay on task more need to know that this behavior is noticed and is not condoned. Your comments can provide clear recognition of skills and give parents insight into areas in which students need to improve. Is well-prepared for class each day.Rushes through work or does not work at an appropriate pace.Never completes assignments in the allotted time.Comprehends well, but needs to work more quickly.Puts her best effort into homework assignments.Stays on task with little supervision.Is a self-motivated student.Sacrifices accuracy for unnecessary speed in his written work.Completes assignments in the time allotted.Avoids careless errors through attention to detail.Uses class time wisely.Needs to keep her cubby and desk better organized. General Learning and Social Skills How a student works with peers and makes friends can be reflective of their personalities, and what they need in order to succeed in life. Your comments should reflect the students abilities to work in groups, individually, and if they are good citizens. Pay attention to how students interact with each other not just in the classroom, but also on the field and at recess, where they often dont feel like the teachers are directly supervising. Needs to be accepting and willing to make new friends.Responds well to positive praise and clear expectations.Is learning to be careful, cooperative, and fair.Works well in groups, planning and carrying out activities.Works democratically with peers.Makes little effort when not under direct supervision.Needs a lot of repetition and practice in order to retain the information given.Shows self-confidence in...Uses a variety of learning strategies to help with...Applies knowledge of...Needs more opportunities to ...Writes clearly and with purpose.Seeks responsibilities and follows through. Helpful Words Here are some helpful words to include in your report card comment section: aggressive, ambitious, anxious, confident, cooperative, dependable, determined, developing, energetic, emerging, friendly, generous, happy, helpful, imaginative, improving, neat, observant, pleasant, polite, prompt, quiet, receptive, reliant, resourceful. Stress the positive attributes and list goals to work on to notify the parents about the negatives. Use words such as requires, struggles, or seldom to show when a child needs extra help. Introduce areas in need of work in a way that wont make parents feel like youre criticizing the student unnecessarily. Addressing Areas in Need of Improvement You can tweak any of the phrases above to indicate an area of improvement by adding the word Needs to. For a more positive spin on a negative comment, list it under a comments section titled goals to work on. For example, for a student who rushes through the work, you might say something like, Needs to focus on trying to do his best work without rushing and having to be the first one finished. Supportive and detailed comments can provide parents with ways to partner with you to make students feel empowered to do better.

Thursday, November 21, 2019

A2 Essay Example | Topics and Well Written Essays - 500 words

A2 - Essay Example Mohamed’s life and teachings were written down, and in the centuries after his death, many scholars wrote interpretations and commentaries, preserving the letter of his teaching as well as explaining its meaning for subsequent generations. As the religion spread, so the Arabic language inevitably spread with it, bringing the values and customs of this region to very different areas. To this day Muslim children are taught to recite verses of the Qur’an, learning the ancient words and preserving the older, classical form of the language which serves as a lingua franca in every country where Islam is an important religion. There is also a great value in preserving the philosophy and literature of previous centuries for modern people to read. The ability to read classical Arabic is a mark of superior education because it represents a prestige form: â€Å"it is a cultural force which unites all Arabs† (Nydell, p. 91). So long as people strive to master this ancient language and culture, they are able to benefit from ancient wisdom and reflect on the common heritage that they share. This linguistic and religious fusion creates unity across the globe, since many Muslims do not speak modern Arabic as their native language, but still learn classical Arabic for religious purposes. In the modern world, therefore, there is a common Arab heritage passed on through the language, especially in the Middle East and North Africa, and this can be seen for example in the giving of certain names to people and places (Suleiman, p. 143). Names such as Mohamed or Ahmed are given to boys in many countries, and this maintains an obvious connection with the ancient heritage of Islam. There is also evidence, however, of the divergence of the spoken language into different dialects, and this has served to differentiate different strands of Arab culture. It has been

Wednesday, November 20, 2019

A Summary of District-Level Downsizing Essay Example | Topics and Well Written Essays - 750 words

A Summary of District-Level Downsizing - Essay Example Schachter goes on to add that, the state legislators or the democratic and republican governors are on a process to balance their budgets and the bad economic times have forced them to implement a huge cut in the public services arena, where the education sector is the target. The director of the AASA (American Association of School Administrators) confirmed this by saying that addition of the cuts to the end of the stimulus year would see the districts come to a cliff. While reacting to the survey that was conducted by the AASA concerning the school superintendents, the director Domenech indicated that the budget cut value of 5%, which was targeting the administrators, was bound to accelerate. The whole district school administrator spectrum has become the target and vulnerable. The cuts in the education sector that are happening currently in the United States cities are a unique event that has never happened. As the number of the students rises, other educational leaders are guttin g departments such as operations and assessments at the district level to turn the assistant principal position into a species that is endangered. The executive director of the IASA (Illinois Association of School Administrators) attributed the current events to the administrators being a microcosm of the recess in America. According to Schachter, different states have reacted to these events in different ways in as much as the cuts or the layoffs are common in all the involved districts. In California for example the layoffs or down sizing have considerably narrowed down the administrative corridor. Approximately 3,000 administrative posts an equivalent of 17% reduction has been implemented in California. This hardest part of this is that the state of California over the same period managed to loose a total of 20,000 teacher’s equivalent of 6%. Despite of all these downsizing attempts a $4billion cut in California state education aid is looming and if the Gov.Brown’s plan of temporarily raising the taxes of some states is not approved, and then as many as 2000 administrators are going out of their jobs next year. The administrators were targeted first to try and salvage the classroom since the instruction of the students was a priority hence the teachers were spared in California. The Charleston (S.C.) to mention as one of the schools froze the salaries of 3400 teachers and lay off a few. The board of this school is planning to cut between 70 and 60 positions in non-classrooms in the following year. This is according to Bobby Michael, who is the chief operations and financial officer for the county school Charleston. (Schachter, 1) In the state of Texas, the idea of raising the property taxes is not being considered despite the amount accounting for 37% of Texas school budget. The superintendent of Irving (Texas) Independent School District Bedden Dana managed to tap $6.5 million, and another $7million to $10 million of the district’s res erve fund will be taken in the following year to cover the deficit. The Irving district is facing a huge deficit of between $21 million to $31 million and, therefore, the reserves will not be enough to offset the deficits. Schachter is of the opinion that, the district has adopted another method of increasing the size of the class by adding three students at the elementary averaging

Sunday, November 17, 2019

MOVEO folding electric scooter Essay Example | Topics and Well Written Essays - 2000 words - 1

MOVEO folding electric scooter - Essay Example 2013). When folded, the scooter assumes a shape not bigger than a suitcase and this makes it easy to even be transported by cars. The main objective of designing this scooter is to ensure that we have environmental friendly operating mode of transport that is affordable (Monika 2013). The core material used in manufacturing of this scooter is carbon fiber build with an organic shape design (Monika 2013). When it comes to technicality, the Moveo scooter can manage speed limit of 35 to 45 km/h since it has an in-build electrical motor with wheels with a battery that lasts over a distance of 35 km (Monika 2013). Notable to mention is the fact that the scooter takes only one hour of charging (Monika. 2013). With this information and after the piloting success, this Hungarian company scheduled for mass production to commence in the year 2014. The costing price for the scooter will be $2000 for the first year with likelihood of prices reducing in the subsequent years (Monika 2013). It is for the above stated objectives that the Antro Group Company required a marketing communication plan for 12 months which will aid in marketing and thereafter selling of the electric scooters (Monika 2013). The marketing plan should incorporate marketing communication strategies and budget of not more than $5 million which is meant to facilitate the entire marketing process (Monika 2013). It should be noted that a successful marketing communication plan is one which integrates all marketing activities (Luther 1992). These are activities that relates to one another within the company’s departments which aims at surrounding the consumer without them knowing that they are being inundated with the conveyed message (Luther 1992). To this effect, the marketing communication plan must serve as the initial foundation of the business marketing plan (Luther 1992). Our vision as Antro Group Company is to provide to the people with alternative affordable mode of transport that

Friday, November 15, 2019

Effect of Glucosamine on Knee Osteoarthritis

Effect of Glucosamine on Knee Osteoarthritis REVIEW OF LITERATURE A prototypical 12-week, double-blind, randomized placebo-controlled trial of glucosamine among subjects with knee osteoarthritis was conducted to present the safety and effectiveness over the Internet. The study comprised 205 subjects aged 45 years or older with symptomatic knee osteoarthritis and their eligibility was authenticated through medical record review. Participants were administered randomly to 1.5 g/d of glucosamine (n101) or placebo (n104), of whom 108 completed the intervention (93 in each arm). The primary outcome measure was the pain subscale of the Western Ontario and McMaster Universities Osteoarthritis Index (Likert version) while additional outcome measures were physical function and stiffness subscales and overall score of the questionnaire, and analgesic use. It was found that there was no difference between treatment and control groups in terms of change in pain score, stiffness, physical function, overall score, and analgesic use. Although glucosamine was appe ared to be safe, it was no more effective than placebo in treating the symptoms of knee osteoarthritis. (McAlindon et al. 2004) A randomized, double-blind, placebo-controlled trial was conducted to evaluate the eficacy of Methylsulfonylmethane (MSM). Fifty men and women with knee OA pain were enrolled in an outpatient medical center. Intervention was MSM 3 g or placebo twice a day for 12 weeks (6 g/day total). Outcomes included the Western Ontario and McMaster University Osteoarthritis Index visual analogue scale (WOMAC), patient and physician global assessments (disease status, response to therapy), and SF-36 (overall health-related quality of life). It was found that MSM produced significant decreases in WOMAC pain and physical function impairment as compared to placebo. MSM also produced improvement in performing activities of daily living when compared to placebo on the SF-36 evaluation. The effectiveness and safety of MSM in managing OA and long-term use could not confirm from this pilot trial, but its potential clinical application was examined. (Kim et al. 2005) A study was carried to evaluate the efficacy and upper gastrointestinal (UGI) safety of celecoxib, compared with nonspecific nonsteroidal anti-inflammatory drugs (NSAIDs), among patients with osteoarthritis. A total of 13,274 osteoarthritis patients from 39 countries were randomly assigned to double-blind treatment with either celecoxib 100 mg twice daily (BID), celecoxib 200 mg BID, or nonselective NSAID therapy (diclofenac 50 mg BID or naproxen 500 mg BID) for 12 weeks. Standard validated measures were used to assess osteoarthritis efficacy. Serious UGI events were evaluated by 2 blinded, independent, gastrointestinal events committees. It was observed that both dosages of celecoxib were as effective as NSAIDs in treating osteoarthritis. However, ulcer complications occurred within the nonselective NSAID group as compared with the celecoxib group. There were less ulcer complications in the celecoxib group compared with the NSAID group, both in patients taking concomitant aspirin an d those not taking aspirin, but the difference reached statistical significance only in the latter comparison. The cardiovascular thromboembolic events were low and not statistically different among the groups, but the study was not powered to detect such differences. It is concluded that celecoxib is as effective as the nonspecific NSAIDs naproxen and diclofenac, but has significantly fewer serious upper gastrointestinal events in the treatment of osteoarthritis. (Singh et al. 2006) The aim of the study was to assess the efficacy of bromelain in treating OA of the knee. The study design was randomized, double-blind placebo controlled trial. Subjects (n ¼47) with a confirmed diagnosis of moderate to severe knee OA were randomized to 12 weeks of bromelain 800 mg/day or placebo, with a 4-week follow-up. Knee (pain, stiffness and function) and quality-of-life symptoms were reported monthly in the WOMAC and SF36 questionnaires, respectively. Adverse events were also recorded. The primary outcome measure was the change in total WOMAC score from baseline to the end of treatment at week 12. Longitudinal models were used to evaluate outcome. No statistically significant differences were observed between groups for the primary outcome, nor the WOMAC subscales or SF36. Both treatment groups showed clinically relevant improvement in the WOMAC disability subscale only. Adverse events were generally mild in nature. This study suggested that bromelain was not efficacious as an adjunctive treatment of moderate to severe OA, but its limitations support the need for a follow-up study. (Brien et al. 2006) The aim of this study was to evaluate and establish the non-inferiority of an oral enzyme therapy as compared to the non-steroidal anti-inflammatory drug (NSAID) diclofenac (DC) in patients with hip osteoarthritis. Ninety patients were treated with osteoarthritis pain for 6 weeks in one study centre in a phase III, randomised, double blind, parallel group trial. The subjects were divided into two groups, 45 patients in each group. The efficacy criteria were assessed by applying the test of non-inferiority with regard to mean changes and frequencies, t-test, U test, ANCOVA and descriptive methods. The non-inferiority of oral enzymes as compared to Diclofenac was established with p = 0.0025. The oral enzymes used were bromelain, trypsin and rutosid. It was found that oral enzymes were simultaneously non-inferior as compared to Diclofenac. However, in case of drug tolerability, some tendencies were observed in favour of oral enzymes. Although, there was no real difference found between oral enzymes and Diclofenac but oral enzymes may well be prescribed for the treatment of hip osteoarthritis. (Klein et al. 2006) The aim of the study was to provide a summary of the actions of curcumin on articular chondrocytes from the available literature with the use of a text-mining tool. Both the potential benefits and drawbacks of using this chemopreventive agent for treating osteoarthritis (OA) were highlighted. Recent work had shown that curcumin protects human chondrocytes from the catabolic actions of interleukin-1 beta (IL-1b) including matrix metalloproteinase (MMP)-3 up-regulation, inhibition of collagen type II and down-regulation of b1-integrin expression. Curcumin also blocks IL-1b-induced proteoglycan degradation, AP-1/NF-kB signalling, chondrocyte apoptosis and activation of caspase-3. The available data in vitro and in vivo studies suggested that curcumin may be a beneficial complementary treatment for OA in humans and companion animals. (Henrotin et al. 2009) The aim of the study was to assess whether glucosamine (GlcN), an oral supplement commonly taken to relieve the symptoms of osteoarthritis, modulates the immune and inflammatory responses to joint injury in organs proximal to GlcN absorption; namely, the liver and the gut-draining lymph nodes. Using a papain-injected knee mouse model, standard histological methods were used to validate our model and document the impact of GlcN (100 mg/kg/day) on groups of C57BL/6 mice (n  ¼ 5). Circulating inflammatory cytokines were assessed by Luminex-based immunoassays and the relevance of this cytokine profile on proteoglycan biosynthesis evaluated using a patellar-cartilage assay. Real-time PCR was used to document the role of the liver in cytokine production. It was observed that Papain significantly degraded the proteoglycans in the injected knees by 2 days. Cartilage proteoglycan content was significantly higher in GlcN-treated, papain-injected knees at Day 14. The peak concentration of ser um pro-inflammatory cytokines occurred earlier and decreased sooner in the injected, GlcN-supplemented mice; this trend was in agreement with the expression of these factors by the liver. GlcN did not alter the percentage of MLN populations but accelerated their activation. Hence, it was suggested that Oral GlcN alters the physiology of the liver and MLNs, which in turn, could indirectly alter the biology of the injured joint. (Panicker et al. 2009) A three month study was conducted on curcumin-phosphatidylcholine phytosome complex. The joint pain was decreased and improvement in joint function was observed in patients suffering from osteoarthritis. The patients were evaluated with clinical endpoints score, Karnofsky Performance Scale Index, and treadmill walking performance and ESR. The significant improvements of both the clinical and biochemical endpoints were observed. (Belcaro et al. 2010) The aim of study was to determine the effect of bromelain treatment on canine articular chondrocytes in vitro. This research was done to evaluate viability of cell, apoptosis levels and mitosis, proteoglycan concentrations and the expression of certain genes. Chondrocytes were exposed to 50 ÃŽ ¼g/ml bromelain for 4, 16 and 32 h. It was found that the rate of apoptosis in the treatment groups was significantly lower than in the control groups. The rate of mitosis in treatment groups was significantly higher than in the control groups. The effect of bromelain on gene expression was measured by the real-time PCR technique. It was found that bromelain significantly decreased TIMP-1 and MMP-3 expression. These experimental bromelain treatments had shown positive results, and increased the process of healing and modulation of osteoarthritis. (Siengdee et al. 2010) The aim of this study was to evaluate that actual cartilage AGE levels were directly related to actual cartilage damage in OA patients. The actual cartilage AGE levels were directly related to actual cartilage damage by use of cartilage obtained at joint replacement surgery. During study, Cartilage and urine samples were obtained from 69 patients undergoing total knee replacement. Samples were analyzed for pentosidine as marker of AGE. Cartilage damage was evaluated macroscopically, histologically, and biochemically. It was found that there was an inverse relation between cartilage AGEs and actual cartilage damage in end-stage OA. This was likely due to ongoing (ineffective) increased turnover of cartilage matrix proteins even in end stage disease. (Vos et al. 2011) The study was done to assess the ability of curcuminoid from Curcuma domestica Val in reducing the cycloxygenase-2 secretion by synovial fluid’s monocytes compared to diclofenac sodium in patients with osteoarthritis. The study was prospective randomized open end blinded evaluation (PROBE). The subjects with knee osteoarthritis were divided into two main groups randomly. One group received 30 mg of curcuminoid thrice a day while other group received 25 mg of diclofenac sodium 3 times in a day. The joints aspiration was carried out and cycloxygenase-2 enzyme secretion by synovial fluid’s monocytes was evaluated by scoring method before and after 4 weeks of treatments. In first group the average scores were 1.84 ±0.37 and 1.15 ±0.28 respectively (pet al. 2012) An observational study was conducted containing a formulation of Curcuma longa and Boswellia serrata extracts. The efficacy and safety of these extracts was measured and directly compared with the celecoxib in osteoarthritis patients. The treatment was tolerated well and it did not produce any major side effects. The patients were analysed by the vital signs, hemogram, liver and renal function tests. This formulation was proved to be effective and safe and no toxicity related with dose was found. (Kizhakkedath 2013) A multicenter, observational and prospective study was carried out on a complex of three natural anti-inflammatory agents. These agents include Harpagophytum procumbens,Curcuma longa, and bromelain nutraceuticals. The purpose of the study was to evaluate the clinical efficacy of commercial complex complex of 3 plant extracts in the treatment of osteoarthritis pain. The patients were divided into two groups i.e. acute and chronic. At baseline, the VAS pain score was 69.1 mm (15.4) and 68.0 mm (18.2) for patients with acute andchronic pain, respectively. At the endpoint, the scores decreased to 42.1 mm (21.1) and 37.8 mm (25.9), respectively. At the endpoint, most of the patients have reached the reduced pain level. No side effects were found due to treatment withdrawals. These 3 plant extracts had excellent tolerance profile and found to be safe alternative of non-steroidal anti-inflammatory drugs (NSAIDs) in patients suffering from osteoarthritis. (Mathieu P et al. 2014) The purpose of this study was to analyse efficacy of extracted Chondroitin Sulfate (CS) from chicken keel cartilages, its comparison with standard CS from shark origin alone and in combination with Glucosamine Sulfate (GS) in developed and standardized papain induced Osteoarthritis (OA) rat model. One group that was control received sterile normal saline solution while other experimental group received papain intra-articularly. Induction of disease with respect to time was assessed on the basis of histological lesions scores. The treatment effectiveness un-treated and treated group was assessed on the basis of histological lesions scores. Treatment was started from 29th day and was continued till 60th day of post papain injection. It was found that histological lesions score was not reduced in cartilages of OA group that remained un-treated. However, structural changes were reduced and were found to be close to the control groups that were treated. Histological lesions score was obse rved highest in un-treated Osteoarthritis group followed by GS treated, standard CS, extracted CS, extracted CS plus GS and standard CS plus GS. There was maximum reduction in histological lesions score in groups treated with combinations. The score of group treated with standard CS (shark) was almost similar to extracted CS (chicken) alone and extracted CS plus GS. CS (chicken) was proved to be effective and beneficial in reducing progression of disease. (Khan et al. 2014) The purpose of this study was to assess the clinical efficacy and safety of oral ginger for symptomatic treatment of osteoarthritis. Inclusion criteria were randomized controlled trials (RCTs) comparing oral ginger treatment with placebo in OA patients aged greater than 18 years. Outcome measures were reduction in pain and disability. The efficacy was measured using Hedges standardized mean difference (SMD), and safety by risk ratio (RR). Standard random-effects meta-analysis was used, and inconsistency was evaluated by the I-squared index (I2). Following ginger intake, a statistically significant pain reduction with a low degree of inconsistency, and a statistically significant reduction in disability were seen, both in favor of ginger. Patients given ginger were more than twice as likely to discontinue treatment compared to placebo. Ginger was found modestly efficacious and reasonably safe for treatment of osteoarthritis. (Bartels et al. 2014) The study was conducted to determine the efficacy and safety of Curcuma domestica extracts in pain reduction and functional improvement. 367 primary knee osteoarthritis patients with a pain score of 5 or higher were randomized to receive ibuprofen 1,200 mg/day or C. domestica extracts 1,500 mg/day for 4 weeks. The main outcomes were Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) total, WOMAC pain, WOMAC stiffness, and WOMAC function scores. Adverse events (AEs) were also recorded. 185 and 182 patients were randomly assigned into C. domestica extracts and ibuprofen groups, respectively. The baseline characteristics were no different between groups. The mean of all WOMAC scores at weeks 0, 2, and 4 showed significant improvement when compared with the baseline in both groups. After using the noninferiority test, the mean difference (95% confidence interval) of WOMAC total, WOMAC pain, and WOMAC function scores at week 4 adjusted by values at week 0 of C. domesti ca extracts were noninferior to those for the ibuprofen group, except for the WOMAC stiffness subscale. The number of events of abdominal pain/discomfort was significantly higher in the ibuprofen group than that in the C. domestica extracts group. Most subjects were satisfied with the treatment, and two-thirds rated themselves as improved in a global assessment. It was concluded that C. domestica extracts are as effective as ibuprofen for the treatment of knee osteoarthritis. The side effect profile was similar but with fewer gastrointestinal adverse events reports in the C. domestica extracts group. (Kuptniratsaikul et al. 2014) The retrospective observational study was conducted to assess the experiences of 820 patients treated with a new Curcuma extract (Flexofytol ®, 4-6 capsules per day), for more than 6 months for various forms of painful osteoarthritis. These experiences were reported by 110 Belgian general practitioners via a questionnaire that included quality-of-life parameters for assessing patient experience. Data were submitted to an independent statistician for analysis. Within the first 6 weeks, Flexofytol ® improved patient pain, articular mobility, and quality of life. Excellent tolerance was reported, and more than half of these patients were able to discontinue analgaesic and anti-inflammatory drugs. Patient satisfaction was confirmed by their decision to maintain Flexofytol ® therapy for more than 6 months. It was found that Flexofytol ® which was based on a new preparation of curcumin, is as a potential neutraceutical for the care of patients complaining of joint problems, with ex cellent tolerance and rapid benefits for articular mobility, pain, and quality of life. (Appelboom et al. 2014)

Tuesday, November 12, 2019

Where to Build a Wind Farm?

In my opinion, the best place to build a wind farm in Cumbria is off the shore of Allonby. This is because; it has a lot of advantages which suit it, for being the best place to build a wind farm; as of its location and ingenious ideology behind it. Moreover, it is an offshore wind farm, which means that it will benefit a lot of homes, as at the sea it is extremely windy. Thus, a lot of electricity is generated, providing a lot of electricity than usual. However, some people would say that, because it is near a town, it’ll be very noisy and distracting to tourists and residents, and will even be an ‘eyesore. On the contrary, the wind farm will be 3 metres away from the land, so there is the least possibility of noise pollution and intervention. Furthermore, some people think that wind farms are quite attractive to look at and would be inquisitive about them when going on holiday. This would bring more tourists to Allonby and make it more popular; are helps the economy by bringing more jobs to Allonby such as information centre employees. This would educate the future generations to elaborate more of wind energy and alternative sources, to help the world’s situation.Also, being it the sea, there is a lot of space to build a wind farm, as there are no other possible variables that could affect it; and the decision to build a wind farm would be eliminated. However, there is the issue of it being in the sea so there is the problem of accessing the wind farm in the first place, if any problems arise with it. If something occurred and there was no way of fixing it as it is in the sea, then the homes and appliances relying on this wind energy, would be without power; and would be very disappointed – a major problem.Notwithstanding, this issue can be sorted out, as it is accessible by either a boat or a helicopter – to try and sort the problem out. However, it won’t be perfect, and sometimes issues may arise, so the government n eeds to think of other ways of access. In addition, the next best choice to build a wind farm would have been, Caldbeck Fells. This is because, it had a lot of advantages as Allonby, however it had some minor points which proved it to be less worthy and eliminated it. Firstly, Caldbeck Fells is on high exposed land which means there is a lot of wind available, which can power a lot of homes in Cumbria and electrical appliances.Also, it is a remote area, meaning no one will be perturbed or disturbed by it; and it will prove beneficial. Exceedingly, it is accessible by country lanes, so if something goes wrong, the maintenance team can access it by car. However, a major factor let it down, which was the fact that; it is just outside a national park, and a national park is preserved for outstanding natural beauty. People say that, if a wind farm were to be built here, then people would be repelled by it and will not choose to visit it – and it may mean the obstruction of birds, wildlife, ecosystems and scenery.However, to reiterate some people may like the idea of watching wind farms, as evidence in Scotland suggests that 8 out of 10 people have said, they would want to find out more about it. Also, it would have made the National Park more popular. Unfortunately, in my opinion, it may be a disadvantage to the fact of, that it may upset ecosystems and wildlife so many ornithologists, animal welfare support groups may protest, demolishing the request to build. Additionally, there were many sites that could’ve qualified for wind farm building, but had a lot of negative factors.Some sites have a lot of space to build wind farms and have a lot of wind availability, so a lot of electricity can be generated like Burgh by Sands. However, it has marshland, and a wind farm cannot be built as of its instability and it is close to a city (Carlisle) which means that, it can possibly disturb tourism activity or increase it, and create noise problems. Also, it wo uld obstruct birds, ecosystems and plants. Besides, Anthorn was on the coast and had some roads, so cars can get through for maintenance, however it had some radio masts and it would interfere with radio signals and be an additional ‘eyesore. Moreover, Skiddaw could’ve had the winning chance, but some factors limited it. It had high ground and plenty of spaces, as there were essentially no buildings and it would not affect anyone in terms of noise, as it was on a high mountain. However, it is part of the Lake District and the famous town Bassenthwaite is next to it; and it can be very unattractive. However, as it being closer to a town, it can provide jobs. Albeit, it cannot be accessible to any transport, as it will be high on a mountain; but a helicopter can be the solution.However, the problem cannot be sorted out as thorough. Wind energy is an excellent alternative energy source, as it doesn’t harm the environment – it just uses wind to drive the turbi nes, which spin around to drive the generator to generate electricity. As for crude oil and fossil fuels, they are running out and also harm the environment. However, this clean energy can very easily be generated. UK has a lot of wind energy up in its highlands, so is ideal for this and wind energy on average provides 2200 GW of energy which is essential for homes, rather than power stations.However, there is not enough land sometimes or not enough wind to drive these turbines which can create an issue; and powerless homes sometimes. So, the government is planning to build offshore wind farms 3 metres off land, which are ideal as here is constantly a lot of wind, generating lots of electricity. It would be ideal to choose offshore wind energy rather than expensive crude oil, as wind energy is renewable and affordable in means of one erected wind turbine can power thousands of homes, and is renewable – so will not run out.Coastal wind farms, also increase tourist activity and are known as peaceful. Momentarily, there is a lot of issue over global warming and crude oil running out. There are issues of sustaining wind power stations in the UK. In my opinion, I believe that, offshore wind farms are the way forward for UK as it will not be any obstruction. However, the government may want to look into other alternatives such as geothermal energy, tidal wave energy – as of a lot of coastal areas. Also, the issue of nuclear power can be looked into, however it may hazardous if something wrong occurs.

Sunday, November 10, 2019

Exploratory essay

There are many students that excel in reading and writing but moieties there are writing challenges that even they come upon on. And with approaching them, are their minds in the most activeness that they can be in? This begins a question of if students were to emphasize all these habits they already have, will that achieve themselves a fuller active mind with greater flexibility in their reading and writing? And is this an idea that all students should be taking an advantage of.Every year we have all these new students entering into their college lives ready to stretch their knowledge and learn all these new techniques in school. Taking with them, everything that have learned in high school and beginning to build more on those things. Learning how to approach all these different challenges and growing towards becoming more intellectual in their writings. But before they can begin to approach these things, they need to find where they stand in reading and writing.To know how well the ir abilities are and what is it that they need to begin working on so that they are ready for the bigger writing challenges that will come before them. Knowing the habits of mind is what is going to help them understand here they stand it will help them improve and position themselves for every new writing assignment they encounter. In high school these habits of mind criteria helped me understand more about where I stand in reading and writing.The habits of mind include things like curiosity and openness where you want to know more and begin to approach things in different ways. This helps me understand that in high school, curiosity and openness is what helped motivated me to seek for answers and explore new ways to find the connections and information I needed. Having engagement and creativity is what gave me that sense to build on the new things I learned and begin to approach things differently.My ability in high school with persistence and responsibility gave me a constant nee d to keep on trying and share my ideas with others and acted upon them. And lastly, the habits of mind include habits of flexibility and metrification. Flexibility helped me recognize different situations and helped me learn how to approach them and metrification is what helped me reflect on everything to improve on the newer things. Knowing these habits of mind criteria has helped me understand what my threaten are and what are the things I need more strength in.We all have different abilities in reading and writing and there are always certain areas that we can improve in. After learning what these habits of minds are, it has shown me that I can become a great writer and I know the places I need to improve on. I do believe that these habits are the pinpoints of becoming a great writer and if we emphasize these points, then it can only bring a bigger improvement for every student in college. It's a foundation that can help people improve in their reading and writing skills and help them have a broaden mind.

Friday, November 8, 2019

Reasons for Joining Fraternity or Sorority

Reasons for Joining Fraternity or Sorority Top Five Reasons To Join A Fraternity Or Sorority New college students have many cool opportunities when they enter the college: from joining a drama club to participating in volunteer work. However, he or she who joins the Greek system will probably have the most fun. And not only because of the wild parties, which most of us imagine after watching Animal House. The reasons for pledging are much more complicated and interesting.Participating can provide you with a lifetime opportunities that can even help you in your professional development later on. People often advance their careers through networking rather than responding to Internet ads. For example, Phi Beta Kappa is the oldest fraternity in the USA. It was formed in 1776 and now has almost three hundred chapters all over the country.Just imagine how the fact that you participated in such a distinguished society will look on your resume. Usually, if you want to join in, you will be recruited during the Rush Week, though in some cases potential members are invited throughout the year. Afterwards, you will probably spend some time as a probationary member, take the pledge and only then will get complete initiation. In accordance with the University of Missouri-Kansas City, the vast majority of the US Presidents were the members of the fraternity. Even if becoming a US president is not a part of your long-term goals, we assure you that becoming a member of the fraternity has a lot of attractive benefits. In our short article, we will make an attempt to analyze the key reasons to join a fraternity or sorority from the academic, social, and professional perspectives. If you are not fully convinced yet, here are several reasons to join Greek life:

Wednesday, November 6, 2019

Production Department Essay Example

Production Department Essay Example Production Department Essay Production Department Essay AS 400 has helped Honda in developing a data warehouse which is stored on DB2. This data warehouse stores all the current and historical data of the organization. Therefore all the data, regardless of its source is consolidated and integrated in one database. For the convenience of each department in Honda, data marts are designed which are basically subsets of data in a data warehouse. These data marts ensure that specific information relevant to each department is readily available to them. The creation of data warehouse and data marts help the employees at different levels in decision making. A range of queries can be run which enable the concerned departments in extracting the required information. The information obtained helps in the generation of reports. SALES DEPARTMENT Honda has just started with its CRM system. It helps Honda with some of the after sales queries and surveys. This also helps to track down its customers. Even though system has been put forward but it’s not fully operated yet. The CRM for example is in a way used on its website. Even though Honda has its website, it is not being used for e-commerce or direct selling of cars. However, a customer can launch his complains here. He would have to submit his complain alongside the car’s bonnet number. With the help of their CRM system Honda will suggest the nearest Honda dealership center to the customer. Honda does not directly deals with its clients. The product distribution channel it chooses is through the car dealers as their middle person or agent. Dealers only work as commission agents and cannot therefore sell the cars on their own. When, a customer places an order at any of the Honda dealer’s showroom, the dealer will notify the Honda’s head office and sales department through e-mail or VPN about the order and its details like color and other features. The sales department generating the orders report will send it to the production department. When the orders are completed according to the information provided to them, the sales department generates the sales receipt and invoice as dealers cannot do it themselves. The receipt will contain the amount of commission to be given to the dealers added on to the car’s base price. The sales department interlinked with MIS, also uses it for generating reports like forecasted sales and trends. These sales forecasting helps them in setting pre-production targets and ordering supplies. The Honda Company orders its spare parts rather than manufacture it at its plant. It uses the system of N-3 or N-4 to order these parts needed for production either 3 or 4 months before, production takes place. This is the part of their SCM. The SCM is usually handled through e-mails with their suppliers. They use excel sheet as their basic ordering format, and use internet as their network of communication with them. APPLICATIONS FOR CUSTOMER RELATION MANAGEMENT A market information system employs procedures and practices to analyze and assess market information gathered from sources inside and outside a firm. Timely market information provides basis for decisions such as product development or improvement and helps a firm manage its customers in a better and efficient way. Honda also uses a web based application, Market Information System, developed on Cisco Systems. This again was in in-house development in mid 2009. Basic purpose of this application is Customer Relation Management (CRM). This is done by collecting customer data, generating reports based on this data and then further by analyzing these reports. MIS is installed at all Honda dealership outlets throughout Pakistan and is also accessible by the sales and marketing departments at the head office. The application is run using Honda’s Virtual Private Network (VPN). Functions of MIS 1. Main Screen: This is the homepage or the index screen after the user logs in using his/her ID for this application. It displays a list of all the activities such as: 1. Pending follow ups 2. Insurance renewals 3. Registration expiry 4. Upcoming customers’ birthdays and anniversaries A bulletin board on this index page consists of the latest news or notifications for sales staff and the dealerships. 1. Data Entry: This module is used to record all the information of any customer interaction i. e. in the form of walk-in, telephone call, sales visit, referral or email inquiry. First a customer interaction form is filled and then this data which consists of fields such as name, contact numbers, birthday, correspondence address and details of car history is entered into the MIS system and according to the customer type, individual or corporate a pink or white card is assigned respectively. How the card system works After the initial cards that are pink and white have been assigned, when a sale is made the operator saves the customer record as sold and converts these cards into yellow card by entering additional information. This clearly creates a distinction between follow up or deferred customers and those to whom a sale has been made. 1. Posting This option allows any operator to put up some information for others or make an announcement on the bulletin board. 1. Report Generation The Reports Menu can generate different reports showing detailed information for the period specified. It is used to drive the statistics of the issues stored in the database based on the required parameters. The following reports can be generated: 1. Follow up report 2. Customer birthday report 3. Customer marriage anniversary report 4. Staff activity report 5. Pending insurance Registration expiry report 1. Inquiries All customer records can be searched through their name, date of data entry, NTN number, NIC number, credit card data, and phone numbers using this data mining module. 1. DONet: To maintain after sales Customer Relation Management, Honda uses DONet. It enables smooth flow of information to the production department in case of any complaint. 1. Handles all the customer data to provide after sales service which includes repairs history, complete car maintenance records and the level of customer satisfaction on each visit to the dealership workshop. 2. In addition to these functions, DONet also maintains the inventory of spare parts and the level is maintained according to the customer demand.

Sunday, November 3, 2019

Cloud computing Essay Example | Topics and Well Written Essays - 750 words

Cloud computing - Essay Example IT gurus administer the fused cloud platforms by means of the advanced knowledge of the virtual servers and the virtualization skills. Infrastructure and applications that promote cloud computing acceptance, attraction of IT Professionals towards cloud computing, and cloud adoption and rejection factors are fundamental. Cloud acceptance: (After reading the slide) let me explain this with the help of a diagram: Organizations that use cloud service can be categorized into three types based on their size; the mega enterprises, the large enterprises, and the medium enterprises. Cloud services used by them are of different kinds including collaboration, software services, desktops and infrastructure, and disaster recovery backup. Here, you can notice that while many enterprises are already using these kinds of services, there is a substantial number of organizations that are considering to use these services, which indicates that cloud computing is growing in popularity. ... nificance and value to the IT implementers because of the benefits its offers that include but are not limited to work efficiencies, support, enhanced productivity, and low-cost initiatives. More benefits of cloud computing are illustrated in the sixth slide. Virtual Infrastructure Cloud computing’s property of virtualization functions most efficiently at the minimization of the cost and complications of the IT operations. There are numerous other advantages that have worked for virtualization that primarily include improved accessibility, virtual maturity, larger data storage capacities, mobility and efficiency. IT executives invest in the cloud initiatives for a variety of reasons including saving money, increased predictability of costs, improved IT customer service, increased productivity, and standardized IT. As you can see in the diagram, the prime motivation behind investing in the cloud initiatives is minimization of cost and saving of money. Increased predictability o f costs and improved IT customer service are equally strong motivators following the saving of money. IT staff supports the cloud initiatives in order to be more efficient, to work with the latest technology, to improve the IT customer service, to maintain a current set of skills, and to minimize the complexity of the job. There is variation among the decision maker and implementer IT staff’s motivations behind supporting the cloud initiatives as evident from the graph. Except for the motivation of keeping the set of skills current, there is a greater number of the decision maker IT staff that is motivated by all of the aforementioned factors as compared to the implementer IT staff. This speaks of the fact that these factors play an important role in the decision making in the IT departments.

Friday, November 1, 2019

Doping in sports Essay Example | Topics and Well Written Essays - 3250 words

Doping in sports - Essay Example Seemingly, he had all figured out. He precisely knew that the venal attitude towards winning excluded the true spirit of sportsmanship and introduced a possibility of cheating, more especially through doping. Indeed, his speech was an act of prophesy because decades after, the sporting activity is saturated with incidences of doping (Burns, 2005). The most hit sporting activity has been the Tour de France cycling competition which drew the full attention of the media to the doping issue (Hoberman, 2007) an issue that had otherwise been covert prior to this. If one ever thinks that doping is a threat to the sporting activity alone then he/she is ultimately mistaken. Based on the sophistication and scope of doping, it poses a threat to more than the world of sport. Initially, doping was considered as a cheating problem but now it has reached proportions that are subject to societal concern. Indeed, as the stakes involved in the sporting activity keep on increasing, the practice continues to be widespread and consequently, the moral values of the sporting activity become questionable and the general health of the sportsmen continue to be under threat and great risk. This paper seeks to assess the issue of doping in sports and how the issue is soon running out of hand and hence the possible remedial steps that can avert the possible doping catastrophe in the sporting world. Therefore, in a bid for the paper to embrace the above scope, the paper will have the following headings; The Problem of Doping in Sports, the Aims and Motivations of the Dopers, Testing for Doping, Doping Testing strategy riddled with Challenges and the Doping Rules as Enforced by the Medical Commission of the IOC. The scope of the problem that doping in sports is, can be shown or be illustrated by looking at a few examples. For instance, in 1986, two pharmacists and a physician were indicted for having sold more than 1000 tablets of Tonedron, at